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Mcl-1-Puma inhibitor 8
CAS No. 678158-55-9
Mcl-1-Puma inhibitor 8 ( Mcl-1-PUMA modulator-8 )
Catalog No. M15591 CAS No. 678158-55-9
Mcl-1-Puma inhibitor 8 is a small-molecule dual-acting compound that targets the apoptotic Mcl-1-PUMA interface with Ki of 0.3 uM (Mcl-1, FPA).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 343 | Get Quote |
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| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameMcl-1-Puma inhibitor 8
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NoteResearch use only, not for human use.
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Brief DescriptionMcl-1-Puma inhibitor 8 is a small-molecule dual-acting compound that targets the apoptotic Mcl-1-PUMA interface with Ki of 0.3 uM (Mcl-1, FPA).
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DescriptionMcl-1-Puma inhibitor 8 is a small-molecule dual-acting compound that targets the apoptotic Mcl-1-PUMA interface with Ki of 0.3 uM (Mcl-1, FPA), reduces multiple cancer cells and inhibits PUMA-mediated apoptosis; a useful chemical probe to achieve safer cancer therapies by modulating Mcl-1-PUMA interaction.
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SynonymsMcl-1-PUMA modulator-8
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PathwayAngiogenesis
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TargetBcl-2
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RecptorBcl-2
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Research Area——
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Indication——
Chemical Information
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CAS Number678158-55-9
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Formula Weight393.51
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Molecular FormulaC22H23N3O2S
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C1N=C(N2CCN(CCO)CC2)S/C1=C\C3=CC=C(C4=CC=CC=C4)C=C3
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Chemical Name5-([1,1'-biphenyl]-4-ylmethylene)-2-(4-(2-hydroxyethyl)piperazin-1-yl)thiazol-4(5H)-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Liu J, et al. Oncotarget. 2017 Apr 20;8(33):54236-54242.
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